Endocrine Abstracts

Introduction: The improvement of vitamin D status is necessary to overcome an impaired calcium-phosphorus metabolism and disturbances in other tissues functioning; safety of medical intervention should include analysis of metabolic changes.Material and methods: Twenty four apparently healthy volunteers 24.9±2 year were included in the study: Group 1 (11/24) with blood serum levels of 25(OH)D <10 ng/ml and Group 2 (13/24) with 25(OH)D levels 10&#...

Abstract: Transsphenoidal surgery is the treatment of choice for Cushing’s disease. Despite the 70–90% remission rates relapses after successful transnasal adenectomy are frequently observed.Aim: To evaluate the dynamics of intra- and early postoperative levels of adrenocorticotrophic hormone (ACTH) and cortizol and their role as predictors or Cushing’s disease remission.Materials/methods: Fifty patients with Cushing...

Background and aims: Hypoglycemia can be a risk factor for adverse cardiovascular and cerebrovascular events. However, changes in platelets and coagulation hemostasis during hypoglycemia have not been extensively studied. During hypoglycemia, a wide spectrum of physiologic responses are activated that could have potential vascular biological effects. To date, the role played by catecholamines, the sympathetic nervous system, and neuroendocrine hormones on activating adhesion m...